What are the best times to fish in regard to the tides, depends on the fish!
For example, for blackfish, I would fish two hours on either side of slack. Even the moon phase is important. I fished on weekend and killed them. You could not leave your hook down for more than two minutes without a fish or loosing your bait. The next week, same spot, very little. Constant taps, but little else. I asked “Crazy” Alberto why. He said, it was a new moon. Confused, I asked what the moon had to do with blackfish in the day time. New and full moon mean faster moving water.
For Fluke you will have the most success two hours of each "high" or "low" tide... that will give your "PRIME" hours to fish.
So, as an example: Assuming that the high tide is at 1:03... Give three hours and you will find the "slack" phase. From there.... 4:03 (slack) you minus 2 hours and that gives you 2:03 - which is a prime time to start your fluking. Then you have the slack... (which is a good time to cast a bucktail and when the water starts to move again.... and you have two more prime water to fish.
Hope this helps. The bottom line is... Do NOT fish the fastest moving waters (high) or (low) tide.
Does this help?