Check out
www.charlestonfishing.com and you can see what is biting then.
There are several great inshore guides and if you do a search for the Isle of Palms Marina they will have some listed there as well.
My favorite is Ben Alderman( Superfly fishing Chaerters).
Good luck and let me know if you need some more names and I can get some for you but there are links/guides that frequent CharlestonFishing.com and all I have ever heard are good reports.
A friend of mine also uses Rick Hiott and has done well with him also